Articles with "inhibition dclk1" as a keyword



Structural Basis of Inhibition of DCLK1 by Ruxolitinib

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22168488

Abstract: Given the functional attributes of Doublecortin-like kinase 1 (DCLK1) in tumor growth, invasion, metastasis, cell motility, and tumor stemness, it is emerging as a therapeutic target in gastrointestinal cancers. Although a series of specific or… read more here.

Keywords: dclk1 ruxolitinib; structural basis; ruxolitinib; basis inhibition ... See more keywords