Insights Into Peptide Inhibition of Alpha-Synuclein Aggregation
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DOI: 10.3389/fnins.2020.561462
Abstract: α-Synuclein (aSyn) aggregation is an attractive target for therapeutic development for a range of neurodegenerative conditions, collectively termed synucleinopathies. Here, we probe the mechanism of action of a peptide 4554W, (KDGIVNGVKA), previously identified through intracellular… read more here.
Keywords: peptide inhibition; aggregation; synuclein; inhibition alpha ... See more keywords
New Insights Into Peptide Cannabinoids: Structure, Biosynthesis and Signaling
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2020.596572
Abstract: Classically, the endocannabinoid system (ECS) consists of endogenous lipids, of which the best known are anandamide (AEA) and 2 arachidonoylglycerol (2-AG), their enzyme machinery for synthesis and degradation and their specific receptors, cannabinoid receptor one… read more here.
Keywords: biosynthesis; cannabinoid receptors; cannabinoids structure; new insights ... See more keywords