Structure‐activity relationship analysis of mitochondrial toxicity caused by antiviral ribonucleoside analogs
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DOI: 10.1016/j.antiviral.2017.04.005
Abstract: Abstract Recent cases of severe toxicity during clinical trials have been associated with antiviral ribonucleoside analogs (e.g. INX‐08189 and balapiravir). Some have hypothesized that the active metabolites of toxic ribonucleoside analogs, the triphosphate forms, inadvertently… read more here.
Keywords: ribonucleoside analogs; mitochondrial toxicity; toxicity; inx 08189 ... See more keywords