Selective nanoparticle-mediated targeting of renal tubular Toll-like receptor 9 attenuates ischemic acute kidney injury.
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DOI: 10.1016/j.kint.2020.01.036
Abstract: We developed an innovative therapy for ischemic acute kidney injury with discerning kidney-targeted delivery of a selective Toll-like receptor 9 (TLR9) antagonist in mice subjected to renal ischemia reperfusion injury. Our previous studies showed that… read more here.
Keywords: kidney injury; ischemic acute; reperfusion; acute kidney ... See more keywords
A synthetic epoxyeicosatrienoic acid analogue prevents the initiation of ischemic acute kidney injury
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DOI: 10.1111/apha.13297
Abstract: Imbalances in cytochrome P450 (CYP)‐dependent eicosanoid formation may play a central role in ischemic acute kidney injury (AKI). We reported previously that inhibition of 20‐hydroxyeicosatetraenoic acid (20‐HETE) action ameliorated ischemia/reperfusion (I/R)‐induced AKI in rats. Now… read more here.
Keywords: acute kidney; ischemic acute; epoxyeicosatrienoic acid; kidney injury ... See more keywords