Variants associated with Bedaquiline (BDQ) resistance identified in Rv0678 and efflux pump genes in Mycobacterium tuberculosis isolates from BDQ naïve TB patients in Pakistan
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DOI: 10.1186/s12866-022-02475-4
Abstract: Background Mutations in the Rv0678 , pepQ and atpE genes of Mycobacterium tuberculosis (MTB) have been reported to be associated with reduced antimycobacterial susceptibility to bedaquiline (BDQ). Resistance conferring mutations in treatment naïve MTB strains… read more here.
Keywords: isolates bdq; resistance; bdq; bdq patients ... See more keywords