Enhanced Immunogenicity of Mitochondrial-Localized Proteins in Cancer Cells
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DOI: 10.1158/2326-6066.cir-19-0467
Abstract: Compared to cytosolic antigens, mitochondrial tumor antigens prime a stronger antitumor immune response, instigated by enhanced cross-presentation and involvement of the STING pathway. Thus, cellular location of tumor antigens is relevant to improved cancer vaccine… read more here.
Keywords: enhanced immunogenicity; immunogenicity mitochondrial; cancer; localized proteins ... See more keywords