A Bioinspired Immunostimulatory System for Inducing Powerful Antitumor Immune Function by Directly Causing Plasma Membrane Rupture
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202305934
Abstract: The Gasdermin protein is a membrane disruptor that can mediate immunogenic pyroptosis and elicit anti‐tumor immune function. However, cancer cells downregulate Gasdermin and develop membrane repair mechanisms to resist pyroptosis. Therefore, an artificial membrane disruptor… read more here.
Keywords: membrane rupture; tumor; immune; membrane ... See more keywords
Nanopipette-Based Nanosensor for Label-Free Electrochemical Monitoring of Cell Membrane Rupture under H2O2 Treatment.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.1c03313
Abstract: H2O2 is an essential signaling molecule in living cells that can cause direct damage to lipids, proteins, and DNA, resulting in cell membrane rupture. However, current studies mostly focus on probe-based sensing of intracellular H2O2,… read more here.
Keywords: membrane rupture; cell; cell membrane; label free ... See more keywords
Pyrazolone-Modified Photosensitizers for Precise Cell Membrane Rupture to Enhance Cancer Immunotherapy.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.5c02764
Abstract: The advancement of immunotherapy aims to achieve complete tumor eradication. However, several critical challenges hinder the efficacy of conventional phototherapy-mediated immune responses, including insufficient immunogenicity and the presence of an immunosuppressive tumor microenvironment. Nonprogrammed cell… read more here.
Keywords: membrane rupture; pyrazolone; cell membrane; immunotherapy ... See more keywords
Determinants of premature membrane rupture among mothers receiving labor care at public hospitals in Northeast Ethiopia: an unmatched case-control study
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DOI: 10.1038/s41598-024-72971-2
Abstract: Premature rupture of membranes is responsible for increased perinatal mortality and neonatal morbidity. Therefore, identifying the determining factors is essential for minimizing its adverse impact. Despite the existence of this problem in the study area,… read more here.
Keywords: membrane rupture; premature membrane; history; care ... See more keywords
The Impact of Antibiotics on Latency When Given at the Time of Membrane Rupture before Viability
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DOI: 10.1055/a-2516-1911
Abstract: Abstract Objective It is well established that antibiotics administered in preterm prelabor rupture of membranes increase latency to delivery. While data are limited for membrane rupture prior to viability, antibiotics may also increase latency in… read more here.
Keywords: prelabor rupture; membrane rupture; rupture membranes; viability ... See more keywords
Favorable neonatal outcome following late-term amniotic membrane rupture with free-floating band: A case report and literature review
Sign Up to like & getrecommendations! Published in 2025 at "Medicine"
DOI: 10.1097/md.0000000000043498
Abstract: Rationale: Amniotic band syndrome (ABS), or amniotic rupture sequence, is a rare congenital condition characterized by fibrous amniotic bands that may entangle fetal parts, leading to constriction, deformities, or even intrauterine demise. However, not all… read more here.
Keywords: membrane rupture; amniotic membrane; band; late term ... See more keywords