The metabolism and hepatotoxicity of ginkgolic acid (17 : 1) in vitro.
Sign Up to like & getrecommendations! Published in 2018 at "Chinese journal of natural medicines"
DOI: 10.1016/s1875-5364(18)30124-9
Abstract: Pharmacological activities and adverse side effects of ginkgolic acids (GAs), major components in extracts from the leaves and seed coats of Ginkgo biloba L, have been intensively studied. However, there are few reports on their… read more here.
Keywords: ginkgolic acid; metabolism; metabolism hepatotoxicity; acid vitro ... See more keywords
Metabolism and Hepatotoxicity of Pyrazinamide, an Antituberculosis Drug
Sign Up to like & getrecommendations! Published in 2021 at "Drug Metabolism and Disposition"
DOI: 10.1124/dmd.121.000389
Abstract: Pyrazinamide (PZA) is an important component of a standard combination therapy against tuberculosis. However, PZA is hepatotoxic, and the underlying mechanisms are poorly understood. Biotransformation of PZA in the liver was primarily suggested behind its… read more here.
Keywords: metabolism; metabolism hepatotoxicity; hepatotoxicity; drug metabolism ... See more keywords