Articles with "methylation markers" as a keyword



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Identification and validation of novel DNA methylation markers for early diagnosis of lung adenocarcinoma

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Published in 2020 at "Molecular Oncology"

DOI: 10.1002/1878-0261.12767

Abstract: Lung cancer has the highest mortality of all cancers worldwide. Epigenetic alterations have emerged as potential biomarkers for early diagnosis of various cancer tissue types. To identify methylation markers for early diagnosis of lung adenocarcinoma,… read more here.

Keywords: lung adenocarcinoma; methylation; dna methylation; methylation markers ... See more keywords
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Universal lung epithelium DNA methylation markers for detection of lung damage in liquid biopsies

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Published in 2022 at "European Respiratory Journal"

DOI: 10.1183/13993003.03056-2021

Abstract: Background Circulating biomarkers for lung damage are lacking. Lung epithelium-specific DNA methylation patterns can potentially report the presence of lung-derived cell-free DNA (cfDNA) in blood, as an indication of lung cell death. Methods We sorted… read more here.

Keywords: methylation; dna; lung; lung epithelium ... See more keywords
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Development of a prognostic risk model for clear cell renal cell carcinoma by systematic evaluation of DNA methylation markers

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Published in 2021 at "Clinical Epigenetics"

DOI: 10.1186/s13148-021-01084-8

Abstract: Background Current risk models for renal cell carcinoma (RCC) based on clinicopathological factors are sub-optimal in accurately identifying high-risk patients. Here, we perform a head-to-head comparison of previously published DNA methylation markers and propose a… read more here.

Keywords: methylation; risk; methylation markers; dna methylation ... See more keywords
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Prognostic DNA methylation markers for renal cell carcinoma: a systematic review.

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Published in 2017 at "Epigenomics"

DOI: 10.2217/epi-2017-0040

Abstract: AIM Despite numerous published prognostic methylation markers for renal cell carcinoma (RCC), none of these have yet changed patient management. Our aim is to systematically review and evaluate the literature on prognostic DNA methylation markers… read more here.

Keywords: renal cell; methylation; prognostic dna; methylation markers ... See more keywords
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Blood-Based Detection of Colorectal Cancer Using Cancer-Specific DNA Methylation Markers

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Published in 2020 at "Diagnostics"

DOI: 10.3390/diagnostics11010051

Abstract: Cancer tissues have characteristic DNA methylation profiles compared with their corresponding normal tissues that can be utilized for cancer diagnosis with liquid biopsy. Using a genome-scale DNA methylation approach, we sought to identify a panel… read more here.

Keywords: dna; methylation markers; colorectal cancer; cancer ... See more keywords