Modulating Conformation of Aβ-Peptide: An Effective Way to Prevent Protein-Misfolding Disease.
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DOI: 10.1021/acs.inorgchem.8b02115
Abstract: Alzheimer's disease (AD) is a typical protein-misfolding disease. Aggregation of amyloid β-peptide (Aβ) plays a key role in the etiology of AD. The misfolding of Aβ results in the formation of β-sheet-rich aggregates and damages… read more here.
Keywords: protein misfolding; misfolding disease; cam; disease ... See more keywords