Articles with "molecular dependencies" as a keyword



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Inferring tumor-specific cancer dependencies through integrating ex vivo drug response assays and drug-protein profiling

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Published in 2022 at "PLoS Computational Biology"

DOI: 10.1101/2022.01.11.475864

Abstract: The development of cancer therapies may be improved by the discovery of tumor-specific molecular dependencies. The requisite tools include genetic and chemical perturbations, each with its strengths and limitations. Drug perturbations can be readily applied… read more here.

Keywords: tumor specific; drug response; molecular dependencies; drug ... See more keywords