Articles with "multiplex enrichment" as a keyword



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Multiplex Enrichment and Detection of Rare KRAS Mutations in Liquid Biopsy Samples using Digital Droplet Pre-Amplification.

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Published in 2019 at "Analytical chemistry"

DOI: 10.1021/acs.analchem.8b01605

Abstract: Oncology research is increasingly incorporating molecular detection of circulating tumor DNA (ctDNA) as a tool for cancer surveillance and early detection. However, noninvasive monitoring of conditions with low tumor burden remains challenging, as the diagnostic… read more here.

Keywords: detection; droplet pre; droplet; pre amplification ... See more keywords