Ganglioside Nanocluster-Targeting Peptidyl Inhibitor Prevents Amyloid β Fibril Formation on the Neuronal Membrane.
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DOI: 10.1021/acschemneuro.2c00047
Abstract: Neurotoxicity caused by peptide and protein aggregates is associated with the onset of neurodegenerative diseases. Accumulation of the amyloid β protein (Aβ) induced by neuronal ganglioside-enriched nanodomains (nanoclusters) in the presynaptic neuronal membrane, resulting in… read more here.
Keywords: ganglioside nanocluster; nanocluster targeting; membrane; formation ... See more keywords