Nickel-Catalyzed Negishi Cross-Coupling of Alkyl Halides, Including Unactivated Tertiary Halides, with a Boron-Stabilized Organozinc Reagent.
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DOI: 10.1021/acs.orglett.3c00051
Abstract: Nickel-catalyzed cross-coupling of unactivated tertiary alkyl electrophiles with alkylmetal reagents is still a challenge. We report herein a nickel-catalyzed Negishi cross-coupling of alkyl halides, including unactivated tertiary halides, with boron-stabilized organozinc reagent BpinCH2ZnI, yielding versatile… read more here.
Keywords: unactivated tertiary; cross coupling; nickel catalyzed; catalyzed negishi ... See more keywords
Computationally Assisted Mechanistic Investigation and Development of Pd-Catalyzed Asymmetric Suzuki-Miyaura and Negishi Cross-Coupling Reactions for Tetra-ortho-Substituted Biaryl Synthesis.
Sign Up to like & getrecommendations! Published in 2018 at "ACS catalysis"
DOI: 10.1021/acscatal.8b02509
Abstract: Metal-catalyzed cross-coupling reactions are extensively employed in both academia and industry for the synthesis of biaryl derivatives for applications to both medicine and material science. Application of these methods to prepare tetra-ortho-substituted biaryls leads to… read more here.
Keywords: miyaura negishi; negishi cross; cross; suzuki miyaura ... See more keywords