Modeling Dendrites and Spatially-Distributed Neuronal Membrane Properties.
Sign Up to like & getrecommendations! Published in 2022 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-89439-9_2
Abstract: The first step toward understanding the brain is to learn how individual neurons process incoming signals, the vast majority of which arrive in their dendrites. Dendrites were first discovered at the beginning of the twentieth… read more here.
Keywords: modeling dendrites; distributed neuronal; neuronal membrane; membrane properties ... See more keywords
Parametric perturbation in a model that describes the neuronal membrane potential
Sign Up to like & getrecommendations! Published in 2019 at "Physica A: Statistical Mechanics and its Applications"
DOI: 10.1016/j.physa.2018.09.160
Abstract: Abstract The Rulkov mapping is a phenomenological model that simulates the changes in the neuronal membrane potential. In this work, we introduce a parametric perturbation in the Rulkov map, that can be related to an… read more here.
Keywords: membrane potential; neuronal membrane; parametric perturbation; model ... See more keywords
Ganglioside Nanocluster-Targeting Peptidyl Inhibitor Prevents Amyloid β Fibril Formation on the Neuronal Membrane.
Sign Up to like & getrecommendations! Published in 2022 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.2c00047
Abstract: Neurotoxicity caused by peptide and protein aggregates is associated with the onset of neurodegenerative diseases. Accumulation of the amyloid β protein (Aβ) induced by neuronal ganglioside-enriched nanodomains (nanoclusters) in the presynaptic neuronal membrane, resulting in… read more here.
Keywords: ganglioside nanocluster; nanocluster targeting; membrane; formation ... See more keywords
Neuronal membrane proteasomes regulate neuronal circuit activity in vivo and are required for learning-induced behavioral plasticity.
Sign Up to like & getrecommendations! Published in 2023 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2216537120
Abstract: Protein degradation is critical for brain function through processes that remain incompletely understood. Here, we investigated the in vivo function of the 20S neuronal membrane proteasome (NMP) in the brain of Xenopus laevis tadpoles. With biochemistry,… read more here.
Keywords: vivo; circuit; plasticity; activity ... See more keywords
Impact of Neuronal Membrane Damage on the Local Field Potential in a Large-Scale Simulation of Cerebral Cortex
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2017.00236
Abstract: Within multiscale brain dynamics, the structure–function relationship between cellular changes at a lower scale and coordinated oscillations at a higher scale is not well understood. This relationship may be particularly relevant for understanding functional impairments… read more here.
Keywords: cerebral cortex; local field; damage; membrane ... See more keywords