The anterior nucleus of the thalamus plays a role in the epileptic network
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51693
Abstract: We investigated both the metabolic differences and interictal/ictal discharges of the anterior nucleus of the thalamus (ANT) in patients with epilepsy to clarify the relationship between the ANT and the epileptic network. read more here.
Keywords: nucleus thalamus; epileptic network; anterior nucleus; thalamus plays ... See more keywords
Deep brain stimulation of the ventralis intermedius nucleus of the thalamus and posterior subthalamic area for Holmes’ tremor secondary to brainstem hemorrhage: A case report
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Neuroscience"
DOI: 10.1016/j.jocn.2018.10.041
Abstract: Holmes' tremor is a rare but severely disabling movement disorder characterized by a combination of resting, action, and intention tremor. Because Holmes' tremor is usually resistant to pharmacotherapy, surgical treatment is required for symptom control… read more here.
Keywords: stimulation; holmes tremor; ventralis intermedius; nucleus thalamus ... See more keywords
Dynorphin Counteracts Orexin in the Paraventricular Nucleus of the Thalamus: Cellular and Behavioral Evidence
Sign Up to like & getrecommendations! Published in 2018 at "Neuropsychopharmacology"
DOI: 10.1038/npp.2017.250
Abstract: The orexin (Orx) system plays a critical role in drug addiction and reward-related behaviors. The dynorphin (Dyn) system promotes depressive-like behavior and plays a key role in the aversive effects of stress. Orx and Dyn… read more here.
Keywords: cocaine; paraventricular nucleus; nucleus thalamus; cocaine seeking ... See more keywords
High-frequency stimulation of anterior nucleus of thalamus desynchronizes epileptic network in humans
Sign Up to like & getrecommendations! Published in 2018 at "Brain"
DOI: 10.1093/brain/awy187
Abstract: Epilepsy has been classically seen as a brain disorder resulting from abnormally enhanced neuronal excitability and synchronization. Although it has been described since antiquity, there are still significant challenges achieving the therapeutic goal of seizure… read more here.
Keywords: anterior nucleus; stimulation; nucleus thalamus; high frequency ... See more keywords
What Should We Expect for Real-World Outcomes of Deep Brain Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy?
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000201455
Abstract: Neurostimulation offers a non-curative approach to treat patients with medication-resistant seizures. In the past 15 years, 2 large, well-designed randomized controlled trials (RCTs) led to the US Food and Drug Administration approval for responsive neurostimulation1… read more here.
Keywords: nucleus thalamus; stimulation anterior; deep brain; real world ... See more keywords
Deep Brain Stimulation of the Anterior Nucleus of the Thalamus in Drug-Resistant Epilepsy in the MORE Multicenter Patient Registry
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000206887
Abstract: Background and Objectives The efficacy of deep brain stimulation of the anterior nucleus of the thalamus (ANT DBS) in patients with drug-resistant epilepsy (DRE) was demonstrated in the double-blind Stimulation of the Anterior Nucleus of… read more here.
Keywords: nucleus thalamus; stimulation anterior; registry; drug resistant ... See more keywords
Optimal targeting of the anterior nucleus of the thalamus for epilepsy: a meta-analysis.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of neurosurgery"
DOI: 10.3171/2022.2.jns212550
Abstract: OBJECTIVE Deep brain stimulation (DBS) of the anterior nucleus of the thalamus (ANT) has been shown to be an effective therapeutic option for select patients with limbic epilepsy. However, the optimal target and electrode position… read more here.
Keywords: nucleus thalamus; dbs; meta analysis; analysis ... See more keywords