Open Search of Peptide Glycation Products from Tandem Mass Spectra.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00388
Abstract: Identification of chemically modified peptides in mass spectrometry (MS)-based glycation studies is a crucial yet challenging task. There is a need to establish a mode for matching tandem mass spectrometry (MS/MS) data, allowing for both… read more here.
Keywords: open search; tandem mass; glycation; peptide glycation ... See more keywords
Optimal Settings of Mass Spectrometry Open Search Strategy for Higher Confidence.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of proteome research"
DOI: 10.1021/acs.jproteome.8b00352
Abstract: In most proteome mass spectrometry experiments, more than half of the mass spectra cannot be identified, mainly because of various modifications. The open search strategy allows for a larger precursor tolerance to utilize more spectra,… read more here.
Keywords: open search; search strategy; search; mass spectrometry ... See more keywords
Open Search-Based Proteomics Reveals Widespread Tryptophan Modifications Associated with Hypoxia in Lung Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2022/2590198
Abstract: The tryptophan residue has a large hydrophobic surface that plays a unique role in the folded protein conformation and functions. Tryptophan modifications are presumably to be readily detected in proteins due to the vulnerability of… read more here.
Keywords: lung cancer; open search; lung; tryptophan modifications ... See more keywords