Polymethoxyflavones from Gardenia oudiepe (Rubiaceae) induce cytoskeleton disruption-mediated apoptosis and sensitize BRAF-mutated melanoma cells to chemotherapy.
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DOI: 10.1016/j.cbi.2020.109109
Abstract: A series of 10 natural and semisynthetic flavonoids (1 to 10) were obtained from Gardenia oudiepe (Rubiaceae), an endemic plant from New Caledonia. Most of them were polymethoxylated flavones (PMFs) of rare occurrence. After a… read more here.
Keywords: apoptosis; oudiepe rubiaceae; cytoskeleton disruption; melanoma cells ... See more keywords