Surface engineering of a Pantoea agglomerans-derived phenylalanine aminomutase for the improvement of (S)-β-phenylalanine biosynthesis.
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DOI: 10.1016/j.bbrc.2019.08.031
Abstract: A Pantoea agglomerans-derived phenylalanine aminomutase (PaPAM) was engineered to improve the biocatalytic synthesis of (S)-β-phenylalanine, which is an important precursor of pharmaceuticals and peptidomimetics. A semi-rational design strategy based on a combination of surface-amino-acid engineering… read more here.
Keywords: engineering; agglomerans derived; derived phenylalanine; phenylalanine ... See more keywords