Articles with "pathological hypertrophy" as a keyword



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Mechanisms of physiological and pathological cardiac hypertrophy

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Published in 2018 at "Nature Reviews Cardiology"

DOI: 10.1038/s41569-018-0007-y

Abstract: Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth. Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual cardiomyocytes increase in size, and the heart develops hypertrophy to… read more here.

Keywords: cardiac hypertrophy; mechanisms physiological; heart; physiological pathological ... See more keywords
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Endothelial Cell-Derived Angiocrines Elicit Physiological Cardiomyocyte Hypertrophy.

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Published in 2019 at "Circulation"

DOI: 10.1161/circulationaha.119.040632

Abstract: Cardiac growth is a major adaptive response to elevated workload on the heart, one that facilitates a decrease in ventricular wall stress and helps sustain pump function.1 Because most mammalian cardiomyocytes become terminally differentiated and… read more here.

Keywords: hypertrophy; growth; cardiomyocyte hypertrophy; heart ... See more keywords