Identification of procathepsin L (pCTS-L)–neutralizing monoclonal antibodies to treat potentially lethal sepsis
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DOI: 10.1126/sciadv.adf4313
Abstract: Antibody-based strategies have been attempted to antagonize early cytokines of sepsis, but not yet been tried to target inducible late-acting mediators. Here, we report that the expression and secretion of procathepsin-L (pCTS-L) was induced by… read more here.
Keywords: sepsis; lethal sepsis; pcts neutralizing; monoclonal antibodies ... See more keywords