Photochemical Internalization Enhanced Nonviral Suicide Gene Therapy.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-8922-5_13
Abstract: Nonviral gene transfection overcomes some of the disadvantages of viral vectors, such as undesired immune responses, safety concerns, issues relating to bulk production, payload capacity, and quality control, but generally have low transfection efficiency. Here… read more here.
Keywords: enhanced nonviral; photochemical internalization; therapy; internalization enhanced ... See more keywords
Photochemical internalization enhanced macrophage delivered chemotherapy.
Sign Up to like & getrecommendations! Published in 2018 at "Photodiagnosis and photodynamic therapy"
DOI: 10.1016/j.pdpdt.2017.12.002
Abstract: BACKGROUND Macrophage (Ma) vectorization of chemotherapeutic drugs has the advantage for cancer therapy in that it can actively target and maintain an elevated concentration of drugs at the tumor site, preventing their spread into healthy… read more here.
Keywords: drug; dox loaded; photochemical internalization; dox ... See more keywords
Endosome Targeting meso-Tetraphenylchlorin-Chitosan Nanoconjugates for Photochemical Internalization.
Sign Up to like & getrecommendations! Published in 2017 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.6b01670
Abstract: Four amphiphilic covalently linked meso-tetraphenylchlorin-chitosan nanoconjugates were synthesized and evaluated for use in photochemical internalization (PCI) in vitro and in vivo. The synthetic protocol for the preparation of two different hydrophobic chlorin photosensitizers, 5-(4-aminophenyl)-10,15,20-triphenylchlorin and… read more here.
Keywords: tetraphenylchlorin chitosan; chitosan; chitosan nanoconjugates; photochemical internalization ... See more keywords
Surface modification of gold nanoparticles with 6-mercapto-1-hexanol to facilitate dual conjugation of protoporphyrin IX and folic acid for improving the targeted photochemical internalization
Sign Up to like & getrecommendations! Published in 2022 at "Iranian Journal of Basic Medical Sciences"
DOI: 10.22038/ijbms.2022.63622.14033
Abstract: Objective(s): Photochemical internalization (PCI) is an important type of photodynamic therapy for delivering macromolecules into the cytosol by the endocytosis process. In this study, 6-mercapto-1-hexanol (MH) was used to functionalize the gold nanostructure as a… read more here.
Keywords: ppix aunp; surface modification; photochemical internalization;
Photochemical Internalization of siRNA for Cancer Therapy
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DOI: 10.3390/cancers14153597
Abstract: Simple Summary The objective of this review is to focus on the different nanovectors capable of transporting genetic material such as small-interfering RNA (siRNA) in order to block the expression of genes responsible for the… read more here.
Keywords: genetic material; therapy; sirna; photochemical internalization ... See more keywords