Effects of sevoflurane and desflurane on the nociceptive responses of substantia gelatinosa neurons in the rat spinal cord dorsal horn: An in vivo patch-clamp analysis
Sign Up to like & getrecommendations! Published in 2020 at "Molecular Pain"
DOI: 10.1177/1744806920903149
Abstract: Background Volatile anesthetics suppress noxiously evoked activity in the spinal dorsal horn, which could contribute in part to analgesia, immobility. Modulation of excitatory and inhibitory synaptic transmission in substantia gelatinosa neurons could lead to the… read more here.
Keywords: substantia gelatinosa; sevoflurane desflurane; dorsal horn; postsynaptic currents ... See more keywords
Metformin inhibits spontaneous excitatory postsynaptic currents in spinal dorsal cord neurons from paclitaxel-treated rats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2023.1191383
Abstract: Introduction Cancer patients treated with paclitaxel often develop chemotherapy-induced peripheral neuropathy, which has not been effectively treated with drugs. The anti-diabetic drug metformin is effective in the treatment of neuropathic pain. The aim of this… read more here.
Keywords: paclitaxel treated; excitatory postsynaptic; spontaneous excitatory; postsynaptic currents ... See more keywords