Abstract A076: Potent and water-soluble C-3’ modified docetaxel analogs by enthalpic driven optimization
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DOI: 10.1158/1535-7163.targ-17-a076
Abstract: A dual strategy aimed at enhancing the binding affinity for microtubules and improving the water solubility of docetaxel led to the design and synthesis of a series of novel C-2 and C-39 modified analogs. Among… read more here.
Keywords: docetaxel analogs; soluble modified; modified docetaxel; water ... See more keywords