Multiomic profiling of the liver across diets and age in a diverse mouse population.
Sign Up to like & getrecommendations! Published in 2021 at "Cell systems"
DOI: 10.1016/j.cels.2021.09.005
Abstract: We profiled the liver transcriptome, proteome, and metabolome in 347 individuals from 58 isogenic strains of the BXD mouse population across age (7 to 24 months) and diet (low or high fat) to link molecular variations… read more here.
Keywords: liver across; mouse population; age; profiling liver ... See more keywords
Metabolic profiling in liver microsomes and mice of E28, a potent FLT3 inhibitor
Sign Up to like & getrecommendations! Published in 2022 at "Xenobiotica"
DOI: 10.1080/00498254.2022.2033882
Abstract: Abstract The objective of this study was to clarify the species differences of metabolic stability of E28 in liver microsomes, and to study metabolic phenotypes of E28 in human liver microsomes by chemical inhibition method.… read more here.
Keywords: profiling liver; liver; liver microsomes; mice e28 ... See more keywords
Proteomic profiling in liver cancer: another new page.
Sign Up to like & getrecommendations! Published in 2019 at "Translational gastroenterology and hepatology"
DOI: 10.21037/tgh.2019.06.03
Abstract: Hepatocellular carcinoma (HCC) is one of the top lethal malignancies worldwide. HCC development is usually asymptomatic and diagnosed at the advanced stage of the disease, at which effective therapeutic options are much limited (1). Multi-kinase… read more here.
Keywords: proteomic profiling; profiling liver; hcc patients; anti pd1 ... See more keywords