Esophageal cancer cells resistant to T-DM1 display alterations in cell adhesion and the prostaglandin pathway
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.24975
Abstract: Trastuzumab-emtansine (T-DM1) is an antibody-drug conjugate that specifically targets HER2 thanks to its antibody component trastuzumab. In spite of responses to this novel agent, acquired resistance to treatment remains a major obstacle. Prolonged in vitro… read more here.
Keywords: prostaglandin pathway; alterations cell; adhesion; cell adhesion ... See more keywords
Molecular Mechanisms Underlying Remodeling of Ductus Arteriosus: Looking beyond the Prostaglandin Pathway
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DOI: 10.3390/ijms22063238
Abstract: The ductus arteriosus (DA) is a physiologic vessel crucial for fetal circulation. As a major regulating factor, the prostaglandin pathway has long been the target for DA patency maintenance or closure. However, the adverse effect… read more here.
Keywords: prostaglandin pathway; pathway; ductus arteriosus; beyond prostaglandin ... See more keywords