Abstract 7545: Epigenetic plasticity in rewiring DNMT1/UHRF1-RB1- NFkB signaling circuit regulates asbestos-induced mesothelial malignant transformation
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DOI: 10.1158/1538-7445.am2024-7545
Abstract: The exact mechanisms underlying the causal relationship between asbestos exposure and malignant mesothelioma (MM) have yet to be elucidated. Widespread genomic and epigenomic alterations are being implicated in rewiring of oncogenic signaling networks which may… read more here.
Keywords: nfkb signaling; dnmt1 uhrf1; rb1 nfkb; signaling circuit ... See more keywords