LAUSR

Retromer dysfunction in amyotrophic lateral sclerosis

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1 Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"

DOI: 10.1073/pnas.2118755119

Abstract: Significance Amyotrophic lateral sclerosis is an adult-onset paralytic disorder whose mechanism remains uncertain. In this work, we report a defect in the retromer complex, which plays a crucial role in endosomal protein sorting and trafficking… read more here.

Keywords: retromer; dysfunction amyotrophic; lateral sclerosis; retromer dysfunction ... See more keywords