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Donor and recipient P450 gene polymorphisms influence individual pharmacological effects of tacrolimus in Chinese liver transplantation patients

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Published in 2018 at "International Immunopharmacology"

DOI: 10.1016/j.intimp.2018.02.005

Abstract: &NA; The immunosuppressant drug tacrolimus (Tac) used for the prevention of immunological rejection is a metabolic substrate of cytochrome P450 enzymes. This study was designed to evaluate the short‐term and long‐term potential influence of single‐nucleotide… read more here.

Keywords: genotype; recipient; donor; pharmacological effects ... See more keywords