EMT signaling: potential contribution of CRISPR/Cas gene editing
Sign Up to like & getrecommendations! Published in 2020 at "Cellular and Molecular Life Sciences"
DOI: 10.1007/s00018-020-03449-3
Abstract: Epithelial to mesenchymal transition (EMT) is a complex plastic and reversible cellular process that has critical roles in diverse physiological and pathological phenomena. EMT is involved in embryonic development, organogenesis and tissue repair, as well… read more here.
Keywords: potential contribution; crispr cas; emt signaling; cas ... See more keywords
PDGFC signaling is a potential therapeutic target for radiation proctopathy.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.e24105
Abstract: e24105Background: Radiation proctopathy(RP), with acute or chronic rectal dysbiosis, arises as one of the most crucial complications of radiation therapy for pelvic malignancies. Common symptoms of... read more here.
Keywords: radiation; pdgfc signaling; therapeutic target; potential therapeutic ... See more keywords
mTOR Signaling and Potential Therapeutic Targeting in Meningioma
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DOI: 10.3390/ijms23041978
Abstract: Meningiomas are the most frequent primary tumors arising in the central nervous system. They typically follow a benign course, with an excellent prognosis for grade I lesions through surgical intervention. Although radiotherapy is a good… read more here.
Keywords: meningioma; potential therapeutic; therapeutic targeting; mtor signaling ... See more keywords
cGMP signaling: a potential therapeutic target for neurodegeneration in glaucoma?
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.360169
Abstract: Neurodegeneration of the central nervous system (CNS) underscores many of humanity’s most debilitating diseases, including Alzheimer’s disease, Parkinson’s disease, and multiple sclerosis. Recently, the nitric oxide-guanylate cyclase-cyclic guanosine monophosphate (NOGC-cGMP) signaling pathway has gained traction… read more here.
Keywords: signaling potential; glaucoma; cgmp; cgmp signaling ... See more keywords