Exercise improves behavioral dysfunction and inhibits the spontaneous excitatory postsynaptic current of D2-medium spiny neurons
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.1001256
Abstract: The abnormal function of striatal medium spiny neurons (MSNs) leads to the excitation-inhibition imbalance of the basal ganglia, which is an important pathogenic factor of Parkinson’s disease (PD). Exercise improves the dysfunction of basal ganglia… read more here.
Keywords: spiny neurons; excitatory postsynaptic; spontaneous excitatory; medium spiny ... See more keywords
Metformin inhibits spontaneous excitatory postsynaptic currents in spinal dorsal cord neurons from paclitaxel-treated rats
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Synaptic Neuroscience"
DOI: 10.3389/fnsyn.2023.1191383
Abstract: Introduction Cancer patients treated with paclitaxel often develop chemotherapy-induced peripheral neuropathy, which has not been effectively treated with drugs. The anti-diabetic drug metformin is effective in the treatment of neuropathic pain. The aim of this… read more here.
Keywords: paclitaxel treated; excitatory postsynaptic; spontaneous excitatory; postsynaptic currents ... See more keywords