Articles with "srg3 overexpression" as a keyword



Chromatin Regulator SRG3 Overexpression Protects against LPS/D-GalN-Induced Sepsis by Increasing IL10-Producing Macrophages and Decreasing IFNγ-Producing NK Cells in the Liver

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms22063043

Abstract: We previously showed that ubiquitous overexpression of the chromatin remodeling factor SWItch3-related gene (SRG3) promotes M2 macrophage differentiation, resulting in anti-inflammatory responses in the experimental autoimmune encephalomyelitis model of multiple sclerosis. Since hepatic macrophages are… read more here.

Keywords: sepsis; lps galn; overexpression; srg3 ... See more keywords