Structural and evolutionary insights into ribosomal RNA methylation.
Sign Up to like & getrecommendations! Published in 2018 at "Nature chemical biology"
DOI: 10.1038/nchembio.2569
Abstract: Methylation of nucleotides in ribosomal RNAs (rRNAs) is a ubiquitous feature that occurs in all living organisms. Identification of all enzymes responsible for rRNA methylation, as well as mapping of all modified rRNA residues, is… read more here.
Keywords: rna methylation; methylation; ribosomal rna; evolutionary insights ... See more keywords
Comparative structural and evolutionary analyses predict functional sites in the artemisinin resistance malaria protein K13
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-47034-6
Abstract: Numerous mutations in the Plasmodium falciparum Kelch13 (K13) protein confer resistance to artemisinin derivatives, the current front-line antimalarial drugs. K13 is an essential protein that contains BTB and Kelch-repeat propeller (KREP) domains usually found in… read more here.
Keywords: protein; comparative structural; k13; artemisinin resistance ... See more keywords
Structural and evolutionary insights into astacin metallopeptidases
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.1080836
Abstract: The astacins are a family of metallopeptidases (MPs) that has been extensively described from animals. They are multidomain extracellular proteins, which have a conserved core architecture encompassing a signal peptide for secretion, a prodomain or… read more here.
Keywords: structural evolutionary; evolutionary insights; zinc; insights astacin ... See more keywords
Structural and Evolutionary Analyses of PR-4 SUGARWINs Points to a Different Pattern of Protein Function
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.734248
Abstract: SUGARWINs are PR-4 proteins associated with sugarcane defense against phytopathogens. Their expression is induced in response to damage by Diatraea saccharalis larvae. These proteins play an important role in plant defense, in particular against fungal… read more here.
Keywords: protein; sugarwins points; evolutionary analyses; analyses sugarwins ... See more keywords