Sudapyridine (WX-081), a Novel Compound against Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.02477-21
Abstract: This study is aimed at chemotherapy for multidrug-resistant tuberculosis (MDR-TB), mainly to develop new anti-TB drugs to kill Mycobacterium tuberculosis, a microorganism with strong drug resistance. In this study, the structure of a potent antituberculosis… read more here.
Keywords: tuberculosis; sudapyridine 081; bdq; resistant tuberculosis ... See more keywords
In vitro and Intracellular Antibacterial Activity of Sudapyridine (WX-081) Against Tuberculosis
Sign Up to like & getrecommendations! Published in 2023 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s390187
Abstract: Background Sudapyridine (WX-081) has exhibited equivalent efficacy than its counterpart parent drug bedaquiline (BDQ) but better safety profile against Mycobacterium tuberculosis (Mtb). Our study was aimed to evaluate in vitro activity of WX-081 against the… read more here.
Keywords: tuberculosis; sudapyridine 081; bdq; activity ... See more keywords