Synthesis and Evaluation of Ginkgolic Acid Derivatives as SUMOylation Inhibitors.
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DOI: 10.1021/acsmedchemlett.0c00353
Abstract: SUMOylation has emerged as an important post-translational modification that has been shown to modulate protein activity associated with various signaling pathways, and consequently, it has emerged as an important therapeutic target. While several natural products… read more here.
Keywords: evaluation ginkgolic; sumoylation; synthesis evaluation; ginkgolic acid ... See more keywords