Synthesis of Sultams and Cyclic N-Sulfonyl Ketimines via Iron-Catalyzed Intramolecular Aliphatic C-H Amidation.
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DOI: 10.1021/acs.orglett.9b01732
Abstract: Cyclic sulfonamides (sultams) play a unique role in drug discovery and synthetic chemistry. A direct synthesis of sultams by an intramolecular C(sp3)-H amidation reaction using an iron complex in situ derived from Fe(ClO4)2 and aminopyridine… read more here.
Keywords: iron catalyzed; synthesis sultams; cyclic sulfonyl; iron ... See more keywords