Molecular Recognition of the Hybrid-Type G-Quadruplexes in Human Telomeres
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DOI: 10.3390/molecules24081578
Abstract: G-quadruplex (G4) DNA secondary structures formed in human telomeres have been shown to inhibit cancer-specific telomerase and alternative lengthening of telomere (ALT) pathways. Thus, human telomeric G-quadruplexes are considered attractive targets for anticancer drugs. Human… read more here.
Keywords: human telomeres; human telomeric; small molecule; telomeric quadruplexes ... See more keywords