YAP/STAT3 promotes the immune escape of larynx carcinoma by activating VEGFR1-TGFβ signaling to facilitate PD-L1 expression in M2-like TAMs.
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DOI: 10.1016/j.yexcr.2021.112655
Abstract: Larynx carcinoma (LC) is the most prevalent head and neck cancer among adults. LC xenograft mouse model was generated to verify the effect of VEGF on macrophage polarization and tumor growth in vivo. EdU assay… read more here.
Keywords: larynx carcinoma; like tams; activating vegfr1; expression ... See more keywords