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General strategies for IgG‐like bispecific antibody purification

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Published in 2024 at "Biotechnology Progress"

DOI: 10.1002/btpr.3515

Abstract: Bispecific antibodies (bsAbs) can simultaneously bind two different antigens or epitopes. Their dual‐targeting capability enables novel mechanisms of action, gaining therapeutic advantages over conventional monospecific mAbs. In recent years, the number of bsAbs grows rapidly… read more here.

Keywords: general strategies; bispecific antibody; igg like; like bispecific ... See more keywords

Cocaine‐ and Amphetamine‐Regulated Transcript Peptide in the Central Nervous System of the Gecko, Hemidactylus leschenaultii: Molecular Characterization, Neuroanatomical Organization, and Regulation by Neuropeptide Y

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Published in 2024 at "Journal of Comparative Neurology"

DOI: 10.1002/cne.25672

Abstract: Neuropeptide cocaine‐ and amphetamine‐regulated transcript (CART) is widely expressed in the brains of teleosts, amphibians, birds, and mammals and has emerged as a conserved regulator of energy balance across these vertebrate phyla. However, as yet,… read more here.

Keywords: regulated transcript; cart; cocaine amphetamine; hemidactylus leschenaultii ... See more keywords
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Newly Diagnosed Classical Hodgkin Lymphoma: Optimizing Outcomes in a New Therapeutic Era

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Published in 2025 at "Hematological Oncology"

DOI: 10.1002/hon.70066

Abstract: The treatment landscape for newly diagnosed classical Hodgkin lymphoma (cHL) has seen remarkable advancements over the past decade, which have been fueled by improved prognostication and response‐adapted techniques, and primarily driven by randomized clinical trials,… read more here.

Keywords: diagnosed classical; classical hodgkin; newly diagnosed; therapeutic era ... See more keywords

The landscape of etiological patterns of hepatocellular carcinoma and intrahepatic cholangiocarcinoma in Thailand

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Published in 2024 at "International Journal of Cancer"

DOI: 10.1002/ijc.35034

Abstract: Thailand is among countries with the highest global incidence and mortality rates of hepatocellular carcinoma (HCC) and intrahepatic cholangiocarcinoma (iCCA). While viral hepatitis and liver fluke infections have been associated with HCC and iCCA, respectively,… read more here.

Keywords: risk; hcc icca; thailand; hepatocellular carcinoma ... See more keywords

Enhanced prognostic evaluation of diffuse large B‐cell lymphoma: A comprehensive surveillance study incorporating Epstein–Barr virus infection status and immunohistochemical markers

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Published in 2024 at "Journal of Medical Virology"

DOI: 10.1002/jmv.29834

Abstract: Emerging biologic subsets and new prognostic markers are significantly important for aggressive diffuse large B‐cell lymphoma (DLBCL). Nevertheless, the high cost of testing limits the availability of these tests in most hospitals, thus making prognostic… read more here.

Keywords: epstein barr; cell lymphoma; cell; diffuse large ... See more keywords
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EBV Infection Alters NK Cell Phenotype Distinctly From hCMV

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Published in 2025 at "Journal of Medical Virology"

DOI: 10.1002/jmv.70620

Abstract: Natural killer (NK) cells are vital in the antiviral response regulated by inhibitory and activating receptors, including NKG2 and KIR families, which bind HLA‐I. While the adaptive features of NK cells in response to human… read more here.

Keywords: hcmv ebv; ebv infection; hla; infection alters ... See more keywords

Infectious complications in CLL/SLL patients receiving Bruton's Tyrosine Kinase inhibitors – systematic review and meta-analysis of randomized controlled trials

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Published in 2025 at "Annals of Hematology"

DOI: 10.1007/s00277-025-06502-y

Abstract: The development of Bruton Tyrosine Kinase inhibitors (BTKis) has revolutionized the management of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL). However, increased infection rates have been reported in patients receiving BTKis in multiple clinical trials. This… read more here.

Keywords: anti cd20; risk; tyrosine kinase; sll patients ... See more keywords

Hodgkin lymphoma: the role of EBV plasma viral load testing in an HIV-endemic setting

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Published in 2024 at "Clinical and Experimental Medicine"

DOI: 10.1007/s10238-024-01524-8

Abstract: South Africa has a high burden of human immune deficiency virus (HIV)-associated Hodgkin lymphoma (HL) which is typically Epstein–Barr virus (EBV) infected, detected by histological stains. Circulating plasma EBV derived from apoptotic EBV infected tumour… read more here.

Keywords: plasma ebv; ebv tumour; ebv; status ... See more keywords

A national, multicenter, retrospective study of human immunodeficiency virus infection-associated lymphoma in China

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Published in 2025 at "Clinical and Experimental Medicine"

DOI: 10.1007/s10238-025-01827-4

Abstract: Since the widespread use of combination antiretroviral therapy, the incidence of opportunistic infections has decreased in HIV infection populations. However, HIV-associated lymphoma become the most common causes of cancer death. Little is known about the… read more here.

Keywords: epidemiology; cohort; hiv associated; lymphoma ... See more keywords

In vitro study on reversible regulation of CAR-T function by Kinsenoside

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Published in 2025 at "Molecular Biology Reports"

DOI: 10.1007/s11033-025-11147-1

Abstract: Chimeric antigen receptor T-cell (CAR-T) therapy has effectively treated various types of malignant tumors. However, effective methods to address its excessive expansion are currently lacking. We aimed to identify a natural compound that can safely… read more here.

Keywords: function; vitro; car; cell ... See more keywords

Mathematical Model of CAR T-Cell Therapy for a B-Cell Lymphoma Lymph Node

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Published in 2024 at "Bulletin of Mathematical Biology"

DOI: 10.1007/s11538-025-01417-1

Abstract: CAR T-cell therapies have demonstrated significant success in treating B-cell leukemia in children and young adults. However, their effectiveness in treating B-cell lymphomas has been limited in comparison to leukemia. In this paper we present… read more here.

Keywords: car cell; cell; mathematical model; cell lymphoma ... See more keywords