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Endocrine Late Effects in Survivors of Cancer in Adolescence and Young Adulthood

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Key Points Question Are adolescent and young adult cancer survivors at increased risk for endocrine diseases? Findings This Danish population-based cohort study that included 32 548 adolescent and young adult cancer… Click to show full abstract

Key Points Question Are adolescent and young adult cancer survivors at increased risk for endocrine diseases? Findings This Danish population-based cohort study that included 32 548 adolescent and young adult cancer survivors shows a 73% higher risk for endocrine diseases in these cancer survivors than a matched cancer-free population. This study shows the patterns of endocrine late effects associated with many cancer sites and how they were modified by patient factors. Meaning This study represents the first step in identifying patients who are at risk for endocrine late effects and indicates the need for surveillance of these patients to prevent the most severe conditions.

Keywords: effects survivors; late effects; endocrine late; cancer survivors; cancer; risk endocrine

Journal Title: JAMA Network Open
Year Published: 2018

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