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Association of Antenatal Steroid Exposure With Survival Among Infants Receiving Postnatal Life Support at 22 to 25 Weeks’ Gestation

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Key Points Question For infants born at the edge of viability who received postnatal life support, was the administration of antenatal steroids associated with higher rates of survival? Finding In… Click to show full abstract

Key Points Question For infants born at the edge of viability who received postnatal life support, was the administration of antenatal steroids associated with higher rates of survival? Finding In a cohort study of 33 472 infants born at 22 to 25 weeks’ gestation between 2012 and 2016, the concordant receipt of antenatal steroids and postnatal life support was significantly associated with higher rates of survival compared with postnatal life support alone. Meaning There is an opportunity for reevaluation of national guidelines, allowing for shared decision making with concordant obstetrical and neonatal treatment plans.

Keywords: postnatal life; life support; weeks gestation

Journal Title: JAMA Network Open
Year Published: 2018

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