Key Points Question Can machine-learning approaches predict opioid overdose risk among fee-for-service Medicare beneficiaries? Findings In this prognostic study of the administrative claims data of 560 057 Medicare beneficiaries, the deep… Click to show full abstract
Key Points Question Can machine-learning approaches predict opioid overdose risk among fee-for-service Medicare beneficiaries? Findings In this prognostic study of the administrative claims data of 560 057 Medicare beneficiaries, the deep neural network and gradient boosting machine models outperformed other methods for identifying risk, although positive predictive values were low given the low prevalence of overdose episodes. Meaning Machine-learning algorithms using administrative data appear to be a valuable and feasible tool for more accurate identification of opioid overdose risk.
               
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