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Evaluation of Machine-Learning Algorithms for Predicting Opioid Overdose Risk Among Medicare Beneficiaries With Opioid Prescriptions

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Key Points Question Can machine-learning approaches predict opioid overdose risk among fee-for-service Medicare beneficiaries? Findings In this prognostic study of the administrative claims data of 560 057 Medicare beneficiaries, the deep… Click to show full abstract

Key Points Question Can machine-learning approaches predict opioid overdose risk among fee-for-service Medicare beneficiaries? Findings In this prognostic study of the administrative claims data of 560 057 Medicare beneficiaries, the deep neural network and gradient boosting machine models outperformed other methods for identifying risk, although positive predictive values were low given the low prevalence of overdose episodes. Meaning Machine-learning algorithms using administrative data appear to be a valuable and feasible tool for more accurate identification of opioid overdose risk.

Keywords: machine; risk; machine learning; opioid overdose; medicare beneficiaries; overdose risk

Journal Title: JAMA Network Open
Year Published: 2019

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