Key Points Question How did prescription analgesic use change among US adults with a potential need for pain management for musculoskeletal conditions from 1999 to 2016? Findings In this repeated… Click to show full abstract
Key Points Question How did prescription analgesic use change among US adults with a potential need for pain management for musculoskeletal conditions from 1999 to 2016? Findings In this repeated cross-sectional analysis of nationally representative data from 7256 adults, opioid and nonopioid analgesic use exhibited reciprocal trends, with decreases in nonopioid analgesic use offset by increases in opioid use. Meaning Substitution of opioids for nonopioid analgesics may have occurred as evidence emerged on the cardiovascular risks associated with nonopioid analgesics, and despite recent decreases, opioid use remained more prevalent in 2016 than in 1999.
               
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