LAUSR

Key Points Question Can a risk score for sustained prescription opioid use after surgery be developed for a working-age population using readily available clinical information? Findings In this case-control study of 86 356 patients undergoing 1 of 10 common surgical procedures, prior opioid exposure was the factor most strongly associated with sustained opioid use. The group with the lowest Stopping Opioids After Surgery scores (<31) had a mean 4.1% risk of sustained opioid use; the group with intermediate scores (31-50) had a mean risk of 14.9%; and the group with the highest scores (>50) had a mean risk of 35.8%. Meaning The scoring system developed in this study may inform the risk of sustained prescription opioid use after surgery and be scalable to clinical practice.