LAUSR

Key Points Question What are the rates of new persistent opioid use among women who receive an opioid prescription after undergoing vaginal or cesarean delivery? Findings In this US national cohort study of 308 226 deliveries, women who received a peripartum opioid prescription had rates of new persistent opioid use of 1.7% for vaginal delivery and 2.2% for cesarean delivery. Prescription size and filling a prescription before delivery were associated with new persistent opioid use. Meaning These results suggest that maternity care clinicians can potentially decrease new persistent opioid use among women after either vaginal or cesarean delivery through judicious opioid prescribing.