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Development of a Machine Learning Model for Survival Risk Stratification of Patients With Advanced Oral Cancer

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Key Points Question Can a machine learning model provide survival risk stratification for patients with advanced oral cancer who have comprehensive clinicopathologic and genetic data? Findings In this 15-year cohort… Click to show full abstract

Key Points Question Can a machine learning model provide survival risk stratification for patients with advanced oral cancer who have comprehensive clinicopathologic and genetic data? Findings In this 15-year cohort study of 334 patients, a risk stratification model using comprehensive clinicopathologic and genetic data accurately differentiated the high-risk group from the low-risk group in postoperative cancer-specific and locoregional recurrenceā€“free survival for patients with advanced oral cancer. Meaning The proposed model demonstrated good discrimination in stratifying patients with different risks of survival by using comprehensive clinicopathologic and genetic data, which can provide additional personalized information for postoperative management of patients with advanced oral squamous cancer.

Keywords: patients advanced; risk stratification; advanced oral; model; cancer

Journal Title: JAMA Network Open
Year Published: 2020

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