LAUSR

Key Points Question What are older women’s perspectives on recommendations for treatment de-escalation for low-risk, early-stage hormone receptor–positive breast cancer? Findings In this qualitative study of 30 participants aged 70 years or older, women expressed skeptical views regarding age-based treatment guidelines, difficulty interpreting the rationale for reducing low-value care to be a favorable rather than poor prognosis, and perceived benefit of some low-value therapies for peace of mind. Meaning Emphasizing an overall favorable prognosis and improving patient education on the risks vs benefits of adjuvant therapies may help reduce overtreatment in older women with early-stage, hormone receptor–positive breast cancer.