LAUSR

Key Points Question Can daily financial incentives for medication adherence induce lasting habits for statin adherence and sustained reductions in low-density lipoprotein cholesterol (LDL-C) levels even after financial incentives are discontinued? Findings In a randomized clinical trial of individuals at elevated risk of cardiovascular disease and with suboptimal cholesterol levels and imperfect adherence, participants in the intervention groups received financial incentives for statin adherence for 6 months. Measured adherence was better among individuals receiving financial incentives, but the change in LDL-C level from baseline to 12 months, the primary outcome, did not differ between intervention and control groups. Meaning Measured improvements in adherence after financial incentives did not translate into improved LDL-C levels.