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Assessment of Trends in Statin Therapy for Secondary Prevention of Atherosclerotic Cardiovascular Disease in US Adults From 2007 to 2016

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Key Points Question What are the use, adherence rate, cost, and outcome trends in statin therapy for secondary prevention of atherosclerotic cardiovascular disease (ASCVD) in US adults from 2007 to… Click to show full abstract

Key Points Question What are the use, adherence rate, cost, and outcome trends in statin therapy for secondary prevention of atherosclerotic cardiovascular disease (ASCVD) in US adults from 2007 to 2016? Findings In this cohort study of data from 284 954 patients, modest increases in statin use, statin adherence rates, and cardiovascular outcomes among patients with ASCVD from 2007 to 2016 were found. The use of high-intensity statins approximately doubled over this time frame. Meaning Results of this study suggest that the increases in statin use, statin adherence rates, and cardiovascular outcomes were modest; and that substantial and persistent treatment gap exists.

Keywords: 2007 2016; prevention atherosclerotic; secondary prevention; statin therapy; therapy secondary; trends statin

Journal Title: JAMA Network Open
Year Published: 2020

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