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Association Between Maternal Prepregnancy Body Mass Index and Anthropometric Parameters, Blood Pressure, and Retinal Microvasculature in Children Age 4 to 6 Years

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Key Points Question Is maternal prepregnancy body mass index (BMI) associated with anthropometric, blood pressure, and retinal vessel parameters in children age 4 to 6 years? Findings In this birth… Click to show full abstract

Key Points Question Is maternal prepregnancy body mass index (BMI) associated with anthropometric, blood pressure, and retinal vessel parameters in children age 4 to 6 years? Findings In this birth cohort study of 240 mother-child pairs, mothers with a higher prepregnancy BMI had children with a significantly higher blood pressure and retinal vessel tortuosity at age 4 to 6 years. These associations were independent of the child’s BMI. Meaning Interventions aiming at a healthy BMI from preconception onwards might improve the cardiovascular health of the next generation.

Keywords: prepregnancy; age years; pressure retinal; blood pressure

Journal Title: JAMA Network Open
Year Published: 2020

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